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Vitamin B12

Vitamin B12

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Vitamin B12 — Research Compound

Vitamin B12, also known as cobalamin, is a water-soluble vitamin extensively studied in laboratory settings for its essential role in cellular metabolism, DNA synthesis, methylation pathways, red blood cell biology, and neurological biochemical processes. Several forms of vitamin B12 exist, including cyanocobalamin, hydroxocobalamin, methylcobalamin, and adenosylcobalamin, each with distinct biochemical characteristics.

At the molecular level, vitamin B12 functions as an essential cofactor for enzymes involved in one-carbon metabolism and fatty-acid and amino-acid metabolism. Of particular research interest are methionine synthase and methylmalonyl-CoA mutase, two B12-dependent enzymes involved in methylation and mitochondrial metabolic pathways.

Scientific literature has extensively examined B12 metabolism, cellular uptake, transport proteins, enzymatic activity, and the biochemical consequences of altered intracellular B12 availability. Research also investigates interactions between vitamin B12, folate metabolism, homocysteine pathways, and DNA synthesis.

This compound is supplied for qualified laboratory research and analytical purposes only.

Product Details

Product Name: Vitamin B12
Alternative Name: Cobalamin
Form: Research compound
Grade: Research use only
Application: Laboratory research and analytical testing only
Storage: Store according to validated laboratory storage specifications and applicable stability documentation. Protect light-sensitive B12 preparations from excessive light exposure.

Research Areas

This compound may be used in research related to:

  • Vitamin B12 metabolism and cellular uptake
  • One-carbon metabolism and methylation pathways
  • Methionine synthase activity
  • Methylmalonyl-CoA mutase pathways
  • DNA synthesis and cellular metabolism
  • Homocysteine and methionine pathway research
  • Mitochondrial metabolic processes
  • Folate and B12 biochemical interactions
  • Cobalamin transport and intracellular processing

Research References

  • Green R, Allen LH, Bjørke-Monsen AL, et al. “Vitamin B12 deficiency.” Nature Reviews Disease Primers. 2017.
  • O’Leary F, Samman S. “Vitamin B12 in health and disease.” Nutrients. 2010.
  • Banerjee R, Ragsdale SW. “The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes.” Annual Review of Biochemistry. 2003.

Important Disclaimer

FOR RESEARCH USE ONLY. NOT FOR HUMAN USE. NOT FOR ANIMAL USE. NOT FOR CONSUMPTION, INJECTION, INGESTION, COSMETIC USE, MEDICAL USE, VETERINARY USE, OR THERAPEUTIC APPLICATION. This product is intended exclusively for controlled laboratory research and analytical purposes. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition and should be handled only by qualified research professionals.

Due to current demand and supply availability, peptide vial cap colors may vary. Cap color is determined by available laboratory packaging materials and does not indicate any difference in product identity, specifications, or quality.

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