5-Amino-1MQ
Product Details
5-Amino-1MQ — Research Compound
5-Amino-1MQ is a small-molecule research compound commonly studied for its interaction with nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular metabolism and energy regulation pathways. In laboratory settings, 5-Amino-1MQ has been investigated for its role in metabolic signaling research, cellular energy expenditure studies, and pathways associated with methylation and NAD+ metabolism.
NNMT is an enzyme that participates in nicotinamide metabolism and has been studied for its relationship to metabolic function, adipose tissue signaling, and cellular energy homeostasis. Research involving NNMT inhibition has explored how modulation of this pathway may influence metabolic processes and biochemical signaling mechanisms in experimental models.
Scientific studies have examined 5-Amino-1MQ and related NNMT inhibitors for their effects on cellular metabolism and energy utilization pathways. Research published in scientific literature has identified NNMT as a potential metabolic regulatory target involved in nicotinamide and methyl donor metabolism.
This compound is supplied for qualified laboratory research and analytical purposes only.
Product Details
Product Name: 5-Amino-1MQ
Form: Research compound
Grade: Research use only
Application: Laboratory research and analytical testing only
Storage: Store in a cool, dry place under proper laboratory storage conditions.
Research Areas
This compound may be used in research related to:
- NNMT (nicotinamide N-methyltransferase) pathway studies
- Cellular metabolism research
- Energy expenditure and metabolic signaling investigation
- NAD+ pathway analysis
- Adipose tissue and metabolic function studies
- Methylation pathway research
- Biochemical and molecular signaling studies
Research References
- Kraus D, Yang Q, Kong D, et al. “Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.” Nature. 2014.
- Neelakantan H, Vance V, Wetzel MD, et al. “Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.” Biochemical Pharmacology.2018.
- Aksoy S, Szumlanski CL, Weinshilboum RM. “Human liver nicotinamide N-methyltransferase.” Journal of Biological Chemistry. 1994.
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